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Accutane (Isotretinoin)
Every third young teenager in the age of 12-18 years has problems with acne. But in some cases acne can develop into the chronic skin condition covering a face, hands, arms, spine and breasts with pimples and furuncles. Such condition is called acne vulgaris and its symptoms can be cured by the innovative medication – Accutane (Isotretinoin).
Off-label and approved indications of Accutane
Accutane is the brand title used for the generic medical substance Isotretinoin. It acts by narrowing the oil glands located in the skin, in such way ceasing the discharge of oil. When patients stop applying Accutane after 4-6 months, the oil glands start growing back, but after the full course most patients see the permanent acne’s elimination.
Accutane is applied for the therapy of harsh acne also called as nodular acne. It can be used for curing skin conditions like skin cancer. The medical preparation acts by delaying the process that causes blemishes to grow. Accutane decreases the oil discharge on skin. In addition to acne, Accutane can be applied to cure facial redness.
Downsides and precautions to Accutane
- Accutane is restricted to people with any severe allergic reactions revealed via skin;
- Make sure you’re not pregnant before beginning using Accutane. This medication can trigger the critical birth defects;
- Accutane can raise the risk of suicidal thoughts which can continue after you cease using it;
- While applying Accutane it is usually advised never apply supplements with vitamin A in order to avert an overdosing risk. It’s not safe to donate blood while applying this medical preparation.
Accutane may be your last hope if you’ve harsh and resistant acne but it does get side consequences like dry skin and hypersensitivity to skin. Infrequently Isotretinoin can raise glucose degrees and affect on the patient’s mood. Rarely Accutane may cause cataracts, difficulties with night vision & extreme depressive condition.
Since such medical preparation is associated with multiple negative consequences, it’s essential to weigh risks and benefits by discussing them with a professional dermatologist. Besides female patients who are sexually active &never use birth control methods should not apply Accutane.
In these scenario females must practice at least two different birth control methods to avert pregnancy – condoms and oral contraceptives.
Drug interactions of Accutane include:
- Acitretin;
- Avage cream;
- Tazarotene;
- Benzoyl peroxide or Adapalene;
- Phenytoin and Carbamazepine;
- Corticosteroids.
What is the best dosage of Accutane?
Accutane is sold in the capsule form. The medical preparation is typically applied during the mealtime, with a full glass of water, twice per 24 hrs. Capsules can be applied whole in order to get the best effect from using them.
You must apply Accutane exactly as assigned. Doses are to be applied orally, with food & approximately at the same time on a daily basis. Food in a stomach helps the medical preparation to be absorbed. Stick to your regimen & commit to it. Accutane’s dosing regimen will usually last during few months. Remember to apply the pill every day.
The usual dosing ranges between 0.5-1.0mg/kg taken on a daily basis. For instance, for someone who weighs about 150 pounds, the dosing will range from about 20-35mg,that has to be applied twice per 24 hrs.
Most patients notice that acne disappears completely after the single treatment. When there is the relapse you may need another course of treatment with the same daily dose. The second course of therapy can be prolonged up to 8 weeks.
Did you know that about Accutane?
86% of people who applied Accutane start noticing the great outcome after the first therapy course, lasting from 4-5 months. More than one therapy course must be assigned to avert any possible relapse of acne vulgaris in future. Although there’s no guarantee when everyone will see the improvement, the majority of Accutane’s users notice how their acne vanish and never come back.
Another interesting fact is that Accutane acts for people with harsh acne which hasn’t responded to anything else featuring oral antibiotics. By the way, you can find this pill in your local drugstore under different titles – Absorica, Claravis, Myorisan, Sotret and Zenatane.